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Performance of the Framingham risk models and pooled cohort equations for predicting 10-year risk of cardiovascular disease: a systematic review and meta-analysis

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Summary of findings

We systematically reviewed the performance of the Framingham Wilson, Framingham ATP III and PCE models for predicting 10-year risk of CHD or CVD for men and women separately in the general population. We found only small differences in pooled performance between the three models, but large differences in performance between validations of the same model across different populations. Although we mostly had to rely on indirect comparisons of the models, we found that performance of all three models was consistently better in women than in men for both discrimination

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