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  • Metalloestrogen uptake, antioxidant modulation and ovotestes development in Callinectes amnicola (blue crab): A first report of crustacea intersex in the Lagos lagoon (Nigeria).

    Posted 2019-12-15 19:39:40 by: The HealthFolk Team

    Related Articles Metalloestrogen uptake, antioxidant modulation and ovotestes development in Callinectes amnicola (blue crab): A first report of crustacea intersex in the Lagos lagoon (Nigeria). Sci Total Environ. 2019 Nov 25;:135235 Authors: Jerome FC, Hassan A, Chukwuka AV PMID: 31831227 [PubMed - as supplied by ...

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  • Molecular detection and antibiotic resistance pattern of extended-spectrum beta-lactamase producing Escherichia coli in a Tertiary Hospital in Enugu, Nigeria.

    Posted 2019-12-15 19:39:40 by: The HealthFolk Team

    Related Articles Molecular detection and antibiotic resistance pattern of extended-spectrum beta-lactamase producing Escherichia coli in a Tertiary Hospital in Enugu, Nigeria. Ann Clin Microbiol Antimicrob. 2019 Dec 12;18(1):41 Authors: Nwafia IN, Ohanu ME, Ebede SO, Ozumba UC Abstract BACKGROUND: The use of antibiotic agents in the treatment of infectious diseases has greatly contributed to the decrease in morbidity and mortality, but these great advances in treatment are being undermined by the rapidly increasing antimicrobial resistant organisms. Extended-spectrum beta-lactamases are enzymes hydrolyzing the beta lactam antibiotics, including third generation cephalosporins and monobactams but not cephamycins and carbapenems. They pose a serious global health threat and have become a challenge for health care providers. The aim of this research was to assess the prevalence of extended-spectrum beta-lactamase producing Escherichia coli in University of Nigeria Teaching Hospital Ituku-Ozalla Enugu and to detect the risk factors for acquisition of the resistant organism. To proffer advice on antibiotic stewardship in clinical practice and public health interventions, to curb the spread of the resistant organisms in the hospital. RESULTS: Out of the 200 E. coli isolates, 70 (35.00%) were confirmed positive for extended-spectrum beta-lactamase production. Fifty-three (75.7%) were from hospital acquired infections. All the isolates were resistant to ampicillin, tetracycline and chloramphenicol while 68 (97.14%) of the 70 isolates were susceptible to imipenem. BlaTEM, blaSHV and blaTEM were detected in 66 (94%) of the 70 isolates. The ESBL bla genes detected were blaCTX-M (n = 26; 37.14%), blaTEM (n = 7; 10.00%), blaSHV (n = 2; 2.86%), blaCTX-M/TEM (n = 7; 10.0%), blaCTX-M/SHV (n = 14; 20.0%) and blaCTX-M/TEM/SHV (n = 10; 14.29%). The three bla genes were not detected in 4 (5.71%) of ...

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  • Impact of dietary patterns, individual and workplace characteristics on blood pressure status among civil servants in Bida and Wushishi communities of Niger State, Nigeria.

    Posted 2019-12-15 19:39:39 by: The HealthFolk Team

    Related Articles Impact of dietary patterns, individual and workplace characteristics on blood pressure status among civil servants in Bida and Wushishi communities of Niger State, Nigeria. PLoS One. 2019;14(12):e0226231 Authors: Obasohan PE, Okorie JN, Sule AL, Ndako KJ Abstract The global burden estimate of hypertension is alarming and results in several million deaths annually. A high incidence of sudden deaths from cardiovascular diseases in the civil workforce in Nigeria is often reported. However, the associations between Dietary Patterns (DPs), individual, and workplace characteristics of hypertension among this workforce have not been fully explored. This study aimed to identify DP in the Bida and Wushishi Communities of Niger State and establish its relationship with hypertension along with other individual and workplace characteristics. Factor analysis was used to establish DP, Chi-square test to identify their relationships with hypertension, and logistic regression to determine the predictor risk factors. The prevalence of hypertension was 43.7%; mean weight, height, and body fat were: 72.8±15 kg, 166±8.9 mm and 30.4%, respectively. Three DPs: "Efficient Diet," "Local diet," and "Energy Boost Diet" were identified. The factor loading scores for these factors were divided into quintiles Q1-Q5; none of them had a significant effect on hypertension status. Conversely, increase in age, the Ministry, Department, and Agency (MDA) of employment, frequency of eating in restaurants, and obesity were identified as significant risk factors. After adjusting for confounders (age, body mass index, MDA, and eating habits), a high score (Q5) in "efficient diet pattern" was significantly related to a lower likelihood of hypertension than a low score (Q1). The prevalence of hypertension among the participants was relatively very high. An increase in age and working in educational sector were risk factors associated ...

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  • The efficacy of intermittent preventive therapy in the eradication of peripheral and placental parasitemia in a malaria-endemic environment, as seen in a tertiary hospital in Abuja, Nigeria.

    Posted 2019-12-15 19:39:39 by: The HealthFolk Team

    Related Articles The efficacy of intermittent preventive therapy in the eradication of peripheral and placental parasitemia in a malaria-endemic environment, as seen in a tertiary hospital in Abuja, Nigeria. Int J Gynaecol Obstet. 2019 Dec 12;: Authors: Umemmuo MU, Agboghoroma CO, Iregbu KC Abstract OBJECTIVE: To determine whether intermittent preventive therapy in pregnancy (IPTp) eradicates peripheral and placental malaria and improves birth weight. METHOD: A cross-sectional study was conducted of 426 pregnant mothers on IPTp with sulphadoxine-pyrimethamine against malaria who presented in labor, at National Hospital Abuja, Nigeria between January and June 2017. The hospital is within the malaria-endemic zone of West Africa. Consenting pregnant women with uncomplicated singleton term pregnancy who had antenatal care in the hospital and lived in the study area for at least 6 months were consecutively recruited. Peripheral and placental blood were collected and examined for malaria parasite by microscopy. Babies were weighed at birth. RESULTS: The prevalence of peripheral malaria parasitemia and placental parasitization were 12.9% (95% confidence interval [CI] 10.0-16.6) and 9.4% (95% CI 7.0-12.7), respectively. Parasite density in both peripheral parasitemia and placental parasitization was low among the women that took IPTp, decreasing with increasing doses, with no parasitemia or parasitization in women that took up to three doses. Birth weight was lower in babies of mothers with plasmodium infestation than in those without infestation (P<0.001, P=0.024). CONCLUSION: IPTp reduces both peripheral parasitemia and placental parasitization, with the capacity to eliminate or prevent them. IPTp also reduces low birth weight. PMID: 31833060 [PubMed - as supplied by ...

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  • Factors Associated with Safe Disposal Practices of Child's Faeces in Nigeria: Evidence from 2013 Nigeria Demographic and Health Survey.

    Posted 2019-12-15 19:39:39 by: The HealthFolk Team

    Related Articles Factors Associated with Safe Disposal Practices of Child's Faeces in Nigeria: Evidence from 2013 Nigeria Demographic and Health Survey. Niger Med J. 2019 Jul-Aug;60(4):198-204 Authors: Aliyu AA, Dahiru T Abstract Background: Stool disposal practices have been shown to be associated with childhood diarrhea. There exist variations in explanatory variables of safe child's faecal disposal practices depending on the context of the study. Thus, the need for this study to assess factors associated with safe disposal practices of children's faeces in Nigeria. Methods: This study utilized the 2013 Nigeria Demographic and Health Survey data. Child's faecal disposal practice was classified as safe and unsafe as defined by the World Health Organization/UNICEF Joint Monitoring Program. Binary and multivariate logistic regression models were used to identify factors associated with safe faecal disposal practices. The analysis was restricted to a weighted sample of 19, 288 youngest children in the households. Results: Overall, the prevalence of safe disposal of child's faeces was 59.4%. Safe child's faeces disposal was the highest among older women (64.4%), highly educated women and their husbands (67.1%) and (66.4%), respectively; among rich households (72.3%), Muslim (68.7%), urban areas (68.8%), and in North West zone (78.4%). In multivariate analysis, safe faecal disposal was significantly associated with the age of mother, maternal education level, wealth index, religion, source of water, and type of toilet facility. Marital status, geopolitical zone, having diarrhea in the past 2 weeks before the survey and sex of the child were not significant determinants of safe faecal disposal practice. Conclusion: Understanding the prevailing faecal disposal practices is a prerequisite to the formulation of effective intervention strategies. It is pertinent, therefore, that programs and ...

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  • Epidemiology and Challenges of Managing Breast Cancer in Keffi, North-Central Nigeria: A Preliminary Report.

    Posted 2019-12-15 19:39:39 by: The HealthFolk Team

    Related Articles Epidemiology and Challenges of Managing Breast Cancer in Keffi, North-Central Nigeria: A Preliminary Report. Niger Med J. 2019 Jul-Aug;60(4):193-197 Authors: Adejumo AA, Ajamu OJ, Akanbi OO, Onwukwe JC, Adeosun OA, Omoregie PO, Amos A, Garba Y, Koroye OF, Garba SE Abstract Background: Breast cancer is now the commonest female malignancy worldwide. The prognosis of such depends on the histopathological type, biological behavior, stage at presentation, availability of adequate oncological services. Aims and Objectives: The aim of this this study is to evaluate the statistics and challenges of breast cancer management in the study centre and compare with other centres. Materials and Methods: This is a prospective, descriptive study that spanned over a period of 4 years (January 2015-December 2018). The study was carried out in the General surgery division of the Surgery Department of the Federal Medical Centre, Keffi. Results: A total of 199 patients were recruited into this study out of which 196 (98.25%) were females and 3 (1.5%) were males. Their age ranged between 20-60 years. The commonest histopathological variant diagnosed is invasive ductal carcinoma (NOS). Early presentation was seen in 54 (<30%) while 145 (>70%) patients had late clinical presentation. Conclusion: Diagnosing and managing breast cancers successfully are mitigated my myriads of factors. Public awareness and provision of adequate care facilities will improve overall survival. PMID: 31831939 ...

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  • Validation of Age Determination with Historical Events in Birnin Kebbi, Northwest Nigeria.

    Posted 2019-12-15 19:39:39 by: The HealthFolk Team

    Related Articles Validation of Age Determination with Historical Events in Birnin Kebbi, Northwest Nigeria. Niger Med J. 2019 Jul-Aug;60(4):190-192 Authors: Otubogun FM, Sanni N, Bello AL Abstract Context: Birth registration is not universal and remains elusive for some people living in developing countries, such as Nigeria; hence, age determination for healthcare and health-related research is often problematic. Aims: The aim is to validate the use of a historical events' scale as a tool for estimating the age of Nigerian adults residing in Birnin Kebbi, Northwest Nigeria. Settings and Design: A cross-sectional survey was conducted in Birnin Kebbi, a metropolitan capital city of Kebbi state, Northwest Nigeria, and included adults aged 18 years and older with a valid document indicating their year of birth. Subjects and Methods: Seven historical events comprising major national events were cross-referenced to the individual's personal history to estimate their ages, which were then compared to their documented ages. Statistical Analysis Used: Relationship of the documented and estimated ages was assessed with the Spearman's rank-order correlation and intraclass correlation coefficient (ICC) analyses. Results: A total of 288 subjects (63.2% males) with a mean documented age of 34.5 ± 11.3 (range 18-75) years were surveyed. The mean estimated age was 32.5 ± 11.18 years. Spearman's rank-order correlation analysis showed a statistically strong positive correlation between the actual and estimated ages (0.953, P < 0.001). The ICC between documented and estimated ages was 0.968 (95% confidence interval = 0.959-0.975). Conclusions: The use of this tool in Nigerian adults provides a reasonably accurate age estimation. Its use in populations and communities with inadequate birth registration may improve the quality of age-related health data in Nigerian adults. ...

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  • A Study on Childhood Epilepsy among Traders in Benin City Nigeria.

    Posted 2019-12-15 19:39:39 by: The HealthFolk Team

    Related Articles A Study on Childhood Epilepsy among Traders in Benin City Nigeria. Niger Med J. 2019 Jul-Aug;60(4):175-180 Authors: Okunola PO, Nwaneri DU Abstract Background: Epilepsy is a serious childhood disease associated with stigmatization in the community. Despite the deleterious effect of the disease on childhood brain growth and development, the disease is treatable. Objective: The aim of this study is to document the knowledge of childhood epilepsy by community members using traders (market women and men in a popular market in Benin City, Nigeria) as a case study. Methodology: This was a descriptive cross-sectional study carried out in April 2018. Data collection was by researcher-administered questionnaire. The respondents were traders (women and men) in Edaiken market Benin City Nigeria who were recruited consecutively during the period of the study. The analysis was performed using the Statistical Package for the Social Sciences version 21, and the level of statistical significance of variables was set at 95% confidence level and P < 0.05. Results: Of the 500 respondents, 47 (9.4%) males and 453 (90.6%) females; mean age (standard deviation) was 35.3 ± 9.4 years. Total knowledge score of childhood epilepsy in this study was 27.6%. Only 116 (23.2%) study participants gave correctly a description of epileptic fits in a child. Although majority 71.0% said that epilepsy has the medical cure, none was able to mention any known drugs for the treatment of epilepsy and 72.6% said that they would use traditional remedies. Conclusion: The overall observed knowledge score of childhood epilepsy was low. Although most respondents stated that epilepsy has medical cure, majority preferred the traditional options for treatment. These findings, therefore, highlighted the need to enlighten the public about childhood epilepsy and its medical treatment options. PMID: ...

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  • Achieving financial risk protection through a national Social Health Insurance Programme in Nigeria: Perspectives of enrollees and healthcare providers.

    Posted 2019-12-15 19:39:38 by: The HealthFolk Team

    Related Articles Achieving financial risk protection through a national Social Health Insurance Programme in Nigeria: Perspectives of enrollees and healthcare providers. Int J Health Plann Manage. 2019 Dec 13;: Authors: Ebunoha GN, Ughasoro MD, Nwakoby IC, Onwujekwe OE Abstract INTRODUCTION: Out-of-pocket (OOP) payment adversely affects universal financial risk protection (UFRP) and the achievement of Universal Health Coverage (UHC). Since the introduction of a Formal Sector Social Health Insurance Programme (FSSHIP) in Nigeria, the extent to which it has provided UFRP is still largely unknown. This study therefore assessed this from the perspectives of both enrollees and healthcare providers. METHODS: The study was undertaken in Enugu state, Nigeria. The subjects were randomly selected primary enrollees and health care providers. An interviewer-administered questionnaire was used for data collection on service utilization under the FSSHIP, as well as out-of-pocket payment of healthcare expenditure. RESULTS: Out of 333 formal sector workers interviewed, 283 (85%) were registered in the FSSHIP and 61.1% of them utilized FSSHIP. Among these, 89.8% of them used OOP to pay for about 95.2% of the healthcare expenditure. From the perspectives of the providers, 97.6%, patients still paid using OOP. CONCLUSION: The FSSHIP is not providing UFRP as expected. This weakens the effectiveness of the FSSHIP to ensure UFRP and ultimately UHC. The NHIS should modify the FSSHIP to provide UFRP and eliminate both the high level of OOP and the proportion of expenditure it covers. PMID: 31837066 [PubMed - as supplied by ...

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  • "I prefer not to have a child than have a HIV-positive child": a Mixed Methods Study of Fertility Behaviour of Men Living with HIV in Northern Nigeria.

    Posted 2019-12-15 19:39:38 by: The HealthFolk Team

    Related Articles "I prefer not to have a child than have a HIV-positive child": a Mixed Methods Study of Fertility Behaviour of Men Living with HIV in Northern Nigeria. Int J Behav Med. 2019 Dec 13;: Authors: Iliyasu Z, Owen J, Aliyu MH, Simkhada P Abstract BACKGROUND: In the era of HIV treatment as prevention, little research has focused on the fertility behaviour of men living with HIV. This study examines the predictors and motivators of fertility among men living with HIV and on antiretroviral treatment in Kano, Nigeria. METHOD: Using mixed methods, structured questionnaires were administered to a clinic-based sample of men living with HIV (n = 270) and HIV-negative/untested controls (n = 270), followed by in-depth interviews with a sub-group of 22 HIV-positive participants. Logistic regression and the framework approach were used to analyse the data. RESULTS: Compared to HIV-negative/untested controls, lower proportions of men living with HIV desired more children (79.3%, n = 214 vs. 91.1%, n = 246, p < 0.05) and intended to bear children within 3 years (57.0%, n = 154 vs. 67.0%, n = 181) (p < 0.05). Marital status (ever married vs. single) predicted fertility intention among men living with HIV (adjusted odds ratio, AOR = 4.70, 95% confidence interval CI, 1.75-13.64) and HIV-negative/untested controls (AOR = 4.23, 95% CI, 1.37-16.45). Men considered self and partner health status, HIV transmission risks, poverty, the effectiveness of interventions, child survival and religion when making fertility decisions. CONCLUSION: Fertility desires remain high post-HIV diagnosis. HIV services should include integrated reproductive health programs that address the fertility desires of clients and include considerations for fertility services. PMID: 31836947 [PubMed - as supplied by ...

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